The protagonist of the Danganronpa/Zero novels. Ryouko is presented as a girl with a neurological disorder which causes her to lose her short and long term memories. Because of this, she writes everything down in a notebook, the "Ryouko Otonashi Memory Notebook". While she has lost her ability to form new memories, she still has her ability to remember and learn 'procedural memory' tasks such as writing and reading.

||Ryouko is actually an amnesiac fake identity of Junko Enoshima. She was created after The Tragedy of Hope's Peak Academy, when Yasuke was asked to interrogate Junko about the incident. Instead, he reluctantly assisted Junko by testing procedures for memory-erasing in preparation for the Killing School Life of 78th Class. Having succeeded in erasing her own memories with Yasuke's memory-erasing technology, Junko assumed the fake identity of Ryouko Otonashi and hid from suspicion. In an attempt to protect her from herself and to protect other people from her, Yasuke attempted to foil Junko's plans by preventing her from regaining her memories. He gave her "treatment" regularly, though in reality he was making sure that her condition stayed the same.||

Ryōko is generally carefree, with a "natural cheerfulness". She has a rather eccentric way of thinking, which is not expressed to be related to her disorder. She is said to have a strange laugh. Because of her forgetfulness, she has trouble concentrating and may come across a bit dumb in other people's eyes. She may often appear uninterested and may fail to respond to situations properly. 

Due to her memory loss, she feels that she is "uninvolved with the world" - at times she barely cares about anything that doesn't concern her or Yasuke, believing that things have nothing to do with her. This is shown most when she is in stressful situations and she constantly repeats, "This has nothing to do with me." Yasuke is the only person she remembers more clearly, though it's only about her feelings towards him instead of any events. This is why she thinks about him almost constantly. While he is rude towards her, she is grateful, because he doesn't treat her with fake sympathy. She isn't worried about her condition either, because she doesn't have anything to compare to due to her memory loss and she sees her forgetfulness as a part of who she is instead of a disadvantage. A sudden cure would be a bigger worry for her, because it would mean separation from Yasuke.

(Source: Danganronpa Wiki, edited)

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